Welcome to the php ebenezer's messageboard
see bottom for more info
But (05/02/22 14:00:55)
Beta lactam antibiotics active against Mycobacterium tuberculosis: AFAIK there is at least one special requirement to be met: They must penetrate the thick lipid-rich bacterial wall - so simple penicillins will not do.
The downside to this is that they are likely to be broad-spectrum antibiotics, so the ecological footprint of a treatment course is likely to be heavy - heavier than the standard anti-TB therapy. Today's and yeaterday's standard therapy: Rifampicin, isoniazid, ethambutol and pyrazinamide - well, the latter three of the four of them are specific against M. tuberculosis. So they do not induce resistance in the normal bacterial flora. Rifampicin is by far the most effective, but just one single mutation, and the drug is inactive.
So I withdraw my wish for an anti-TB beta lactam. I don't believe it is practical or useful. Sorry.
- mbs.php3[?TPP=00] : Show first main page with up to TPP threads
- mbs.php3?thread=xx[&TPP=00] : Show the main page which include thread XX with up to TPP threads
- mbs.php3?thread=xx&num=yy : Show post xx and its corresponding thread
- mbs.php3?thread=xx&expand=on : Show all post in Thread on a single html page (usefull to keep a local copy)
messageboard's PHP script is a courtesy of Laurent
| ||This board has been visited 197688 times||Current time is 27/05/22 06:20:13|